Centre Hospitalier Universitaire Montpellier (France)
CHRUM is a tertiary-care academic hospital with a specialized research team in the application of in vivo and in vitro tests for drug allergy patients and expertise in the development of diagnostic algorithms.
• WP3: CHRUM will collaborate in WP3 sample selection, compounds synthesis and development. CHRUM will be mainly devoted to:
i. Identifying well-characterized BLC allergic patients ii. Obtaining serum samples from BLC allergic patients
• WP5: The participation of CHRUM will consist of the evaluation of the final device in a preindustrial trial assessing its sensitivity, specificity, positive and negative predictive values in the diagnosis of IgE mediated BLC allergy, and more specifically to:
i. Provide new serum samples from BLC allergic patients ii. Evaluate the performance of the final device in the diagnosis of the selected cases of IgE-mediated BLC allergy iii. Evaluate the different patterns of BLC IgE recognition depending of the type of allergic reaction iv. Contribute to assay methodology development to optimize its use in diverse clinical settings.
• Participation in WP6 Exploitation and Dissemination. • WP7 CHRUM will take part in project management activities.